Reduced Structural Connectivity of a Major Frontolimbic Pathway in Generalized Anxiety Disorder

Wednesday, September 05, 2012 Do Tromp 0 Comments

Check out our new study that just got published in Archives of General Psychiatry:
"A new University of Wisconsin-Madison imaging study shows the brains of people with generalized anxiety disorder (GAD) have weaker connections between a brain structure that controls emotional response and the amygdala, the Uncinate Fasciculus, which suggests the brain's "panic button" may stay on due to lack of regulation."

Here you get an impression of how we traced the Uncinate Fasciculus in all the 88 subjects. You can see a three-dimensional rendering of the Uncinate Fasciculus and the 4 seed areas, overlaid on a Fractional Anisotropy map for a single subject.